DCN Antibody, FITC conjugated

Rare Species
Code CSB-PA006554LC01BO
Size US$166
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Product Details

Full Product Name
Rabbit anti-Bos taurus (Bovine) DCN Polyclonal antibody
Uniprot No.
Target Names
Alternative Names
DCN antibody; Decorin antibody; Bone proteoglycan II antibody; PG-S2 antibody
Raised in
Rabbit
Species Reactivity
Bovine
Immunogen
Recombinant Bovine Decorin protein (31-360AA)
Immunogen Species
Bos taurus (Bovine)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
May affect the rate of fibrils formation.
Gene References into Functions
  1. downregulation associated with proliferation, remodeling and vascularization of placental tissues PMID: 25012297
  2. The inclusion of decorin proteoglycan during fibrillogenesis of type I collagen increases the modulus and tensile strength of resulting collagen gels. PMID: 23608680
  3. These findings reveal a novel role of DCN as an antagonistic ligand for VEGFR-2. PMID: 21659473
  4. Data show that biglycan, collagen type I, collagen type II, decorin, and versican were significantly affected by vibration duration, frequency, and amplitude. PMID: 20386503
  5. Results suggest that decorin contributes to the formation and stabilization of collagen fibres in the perimysium that support muscle fibres assembled with myogenesis. PMID: 12097842
  6. decorin is a dimer in solution PMID: 12601001
  7. decorin-induced fibroblast cytoskeletal and signalling changes result in an increased cell migration; potential role in the remodelling process PMID: 14600270
  8. Transduced bovine decorin synthesized de novo by rat arterial smooth muscle cells increases type I collagen synthesis and enhances contraction of collagen gels. PMID: 14615389
  9. The results indicate that CTGF suppresses the synthesis of biglycan but newly induced that of decorin in the cells when the cell density is low. PMID: 15313168
  10. crystal structure of the dimeric protein core PMID: 15501918
  11. a novel collagen binding domain in decorin acts cooperatively with leucine-rich repeat 4 to mask the alpha2beta1 integrin-binding site on collagen, an important sequence for the phagocytosis of collagen fibrils PMID: 15811857
  12. The rupture force of single bonds between decorins (GAG chains interaction) was determined directly as 16.5+/-5.1 pN using a laser tweezers/interferometer single molecular nanomechanical testing system. PMID: 16263082
  13. analysis of decorin from different bovine tissues PMID: 16293388

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Subcellular Location
Secreted, extracellular space, extracellular matrix.
Protein Families
Small leucine-rich proteoglycan (SLRP) family, SLRP class I subfamily
Database Links
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